方仁东
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方仁东，男，博士，副教授，研究生导师。
*学习工作经历:
2014/04至今，西南大学mobile288-365，副教授，研究生导师；
2014/03 京都大学(日本)，基础医学院微生物学专业，博士；
2008/07 西南大学，预防兽医学，硕士；
2005/07 西南大学，mobile288-365动物医学专业，本科。
2014/04至今，西南大学mobile288-365，副教授，研究生导师；
2014/03 京都大学(日本)，基础医学院微生物学专业，博士；
2008/07 西南大学，预防兽医学，硕士；
2005/07 西南大学，mobile288-365动物医学专业，本科。
*研究生招生专业及方向:
090602预防兽医学
-03兽医公共卫生
090602预防兽医学
-03兽医公共卫生
*主要学术论文：
发表学术论文10余篇, 代表性论文在《自然-免疫学》，《免疫学杂志》，《感染与免疫》，《临床微生物学杂志》 （Nature Immunology，Journal of Immunology，Infection and Immunity, Journal of Clinical Microbiology）等SCI杂志发表。经教育部科技查新工作站检索，截止2016年10月，方仁东发表的SCI收录论文，共被SCI他引323 次，SCI他引期刊227种次，SCI他引作者1520人次；其中第一作者论文被SCI他引123次，SCI他引期刊83种次，SCI他引作者750人次；非第一作者论文被SCI他引200次，SCI他引期刊144种次，SCI他引作者770人次。代表性学术论文如下：
(1) Hideki Hara#, Kohsuke Tsuchiya#, Ikuo Kawamura, Rendong Fang, Eduardo Hernandez-Cuellar, Yanna Shen, Junichiro Mizuguchi, Edina Schweighoffer, Victor Tybulewicz, Masao Mitsuyama*, Syk- and JNK-mediated ASC phosphorylation acts as a molecular switch controlling the formation of speck-like aggregates upon inflammasome activation. Nature Immunology. 2013, 14(12):1247-1255. (IF=24.973, SCI他引59次)
发表学术论文10余篇, 代表性论文在《自然-免疫学》，《免疫学杂志》，《感染与免疫》，《临床微生物学杂志》 （Nature Immunology，Journal of Immunology，Infection and Immunity, Journal of Clinical Microbiology）等SCI杂志发表。经教育部科技查新工作站检索，截止2016年10月，方仁东发表的SCI收录论文，共被SCI他引323 次，SCI他引期刊227种次，SCI他引作者1520人次；其中第一作者论文被SCI他引123次，SCI他引期刊83种次，SCI他引作者750人次；非第一作者论文被SCI他引200次，SCI他引期刊144种次，SCI他引作者770人次。代表性学术论文如下：
(1) Hideki Hara#, Kohsuke Tsuchiya#, Ikuo Kawamura, Rendong Fang, Eduardo Hernandez-Cuellar, Yanna Shen, Junichiro Mizuguchi, Edina Schweighoffer, Victor Tybulewicz, Masao Mitsuyama*, Syk- and JNK-mediated ASC phosphorylation acts as a molecular switch controlling the formation of speck-like aggregates upon inflammasome activation. Nature Immunology. 2013, 14(12):1247-1255. (IF=24.973, SCI他引59次)
(2) Rendong Fang, Hideki Hara, Shunsuke Sakai, Eduardo Hernandez-Cuellar, Masao Mitsuyama, Ikuo Kawamura, Kohsuke Tsuchiya*, Type I Interferon Signaling Regulates Activation of the Absent in Melanoma 2 Inflammasome during Streptococcus pneumoniae Infection, Infection and Immunity, 2014, 82(6):2310-2317 (IF=3.731, SCI他引14次)
(3) Rendong Fang, Kohsuke Tsuchiya*, Ikuo Kawamura, Yanna Shen, Hideki Hara, Shunsuke Sakai, Takeshi Yamamoto, Teresa Fernandes-Alnemri, Ruili Yang, Eduardo Hernandez-Cuellar, Sita R. Dewamitta, Yanting Xu, Huixin Qu, Emad S.Alnemri, and Masao Mitsuyama, Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection, Journal of Immunology, 2011, 187:4890-4899. (IF=5.788, SCI他引46次)
(4) Rendong Fang, Xia Li, Lin Hu, Qimin You, Jing Li, Jie Wu, Peng Xu, Huayan Zhong, Ying Luo, Jian Mei, Qian Gao*, Cross-priming amplification for rapid detection of Mycobacterium tuberculosis in sputum specimens, Journal of clinical microbiology, 2009, 47(3): 845-847.(IF=4.162, SCI他引47次)
(5) Rendong Fang, Xia Li, Jing Li, Jie Wu, Xin Shen, Xiaohong Gui, Kathryn DeRiemer, Li Liu, Jian Mei, Qian Gao, Mixed Infections of Mycobacterium tuberculosis in Tuberculosis Patients in Shanghai, China. Tuberculosis. 2008 Sep;88(5):469-73. (IF=1.758, SCI他引16次)
(6) Huihui Du#, Rendong Fang#, Tingting Pan, Tian Li, Nengzhang Li, Qiang He, Rui Wu, Yuanyi Peng*, Zeyang Zhou*, Comparative Genomics Analysis of Two Different Virulent Bovine Pasteurella multocida Isolates, International Journal of Genomics, 2016: 4512493 (共同第一作者，IF=1.8)
(5) Rendong Fang, Xia Li, Jing Li, Jie Wu, Xin Shen, Xiaohong Gui, Kathryn DeRiemer, Li Liu, Jian Mei, Qian Gao, Mixed Infections of Mycobacterium tuberculosis in Tuberculosis Patients in Shanghai, China. Tuberculosis. 2008 Sep;88(5):469-73. (IF=1.758, SCI他引16次)
(6) Huihui Du#, Rendong Fang#, Tingting Pan, Tian Li, Nengzhang Li, Qiang He, Rui Wu, Yuanyi Peng*, Zeyang Zhou*, Comparative Genomics Analysis of Two Different Virulent Bovine Pasteurella multocida Isolates, International Journal of Genomics, 2016: 4512493 (共同第一作者，IF=1.8)
(7) Kohsuke Tsuchiya#, Hideki Hara, Rendong Fang, Eduardo Hernandez-Cuellar, Shunsuke Sakai, Sylvia Daim, Xi Chen, Sita R. Dewamitta, Huixin Qu, Masao Mitsuyama, Ikuo Kawamura, The adaptor ASC exacerbates lethal Listeria monocytogenes infection by mediating IL-18 production in an inflammasome-dependent and -independent manner. European Journal of Immunology. 2014 Dec; 44(12):3696-3707. (IF=4.034, SCI他引3次)
(8) Ruili Yang, Chen Xi, Dewamitta R. Sita, Shunsuke Sakai, Kohsuke Tsuchiya, Hideki
Hara, Yanna Shen, Huixin Qu, Rendong Fang, Masao Mitsuyama, Ikuo Kawamura*, The RD1 locus in the Mycobacterium tuberculosis genome contributes to the maturation and secretion of IL-1α from infected macrophages through the elevation of cytoplasmic calcium levels and calpain activation. Pathogens and Disease. 2014 Feb; 70(1):51-60. (IF=2.403, SCI他引4次)
Hara, Yanna Shen, Huixin Qu, Rendong Fang, Masao Mitsuyama, Ikuo Kawamura*, The RD1 locus in the Mycobacterium tuberculosis genome contributes to the maturation and secretion of IL-1α from infected macrophages through the elevation of cytoplasmic calcium levels and calpain activation. Pathogens and Disease. 2014 Feb; 70(1):51-60. (IF=2.403, SCI他引4次)
(9) Eduardo Hernandez-Cuellar, Kohsuke Tsuchiya*, Hideki Hara, Rendong Fang, Shunsuke Sakai, Ikuo Kawamura, Shizuo Akira, Masao Mitsuyama, Nitric Oxide Inhibits the NLRP3 Inflammasome. Journal of Immunology. 2012 Dec 1; 189(11):5113-5117. (IF=5.52, SCI他引55次)
(10) Takeshi Yamamoto, Hideki Hara, Kohsuke Tsuchiya, Shunsuke Sakai, Rendong Fang, Motohiro Matsuura, Takamasa Nomura, Fumihiko Sato, Masao Mitsuyama, Ikuo Kawamura*, Listeria monocytogenes Strain-specific Impairment of the TetR Regulator Underlies the Drastic Increase in Cyclic di-AMP Secretion and Interferon β-Inducing Ability. Infection and Immunity. 2012 Jul; 80(7):2323-2332. (IF=4.074, SCI他引19次)
(10) Takeshi Yamamoto, Hideki Hara, Kohsuke Tsuchiya, Shunsuke Sakai, Rendong Fang, Motohiro Matsuura, Takamasa Nomura, Fumihiko Sato, Masao Mitsuyama, Ikuo Kawamura*, Listeria monocytogenes Strain-specific Impairment of the TetR Regulator Underlies the Drastic Increase in Cyclic di-AMP Secretion and Interferon β-Inducing Ability. Infection and Immunity. 2012 Jul; 80(7):2323-2332. (IF=4.074, SCI他引19次)
(11) Tsuchiya K, Hara H, Kawamura I, Nomura T, Yamamoto T, Daim S, Dewamitta SR, Yannan Shen , Rendong Fang, Mitsuyama M. Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes. Journal of Immunology. 2010 Jul 15;185(2):1186-95. (IF=5.745,SCI他引60次)
(12) Huihui Du#, Chenlu Wu#, Chunming Li, Rendong Fang, Jianwei Ma, Jiale Ji, Zhihong Li, Nengzhang Li, Yuanyi Peng*, Zeyang Zhou*, Two novel cross-protective antigens for bovine Pasteurella multocida, Molecular Medicine Reports（2017, 已接收）
(12) Huihui Du#, Chenlu Wu#, Chunming Li, Rendong Fang, Jianwei Ma, Jiale Ji, Zhihong Li, Nengzhang Li, Yuanyi Peng*, Zeyang Zhou*, Two novel cross-protective antigens for bovine Pasteurella multocida, Molecular Medicine Reports（2017, 已接收）
*联系方式：
通讯地址：重庆市北碚区天生路2号西南大学mobile288-365，400715
电话：023-68251196（办）
传真：023-68251196
QQ： 980909449
E-mail: frend023@hotmail.com
通讯地址：重庆市北碚区天生路2号西南大学mobile288-365，400715
电话：023-68251196（办）
传真：023-68251196
QQ： 980909449
E-mail: frend023@hotmail.com
